Based on the popular film starring Brad Pitt and Angelina Jolie, Mr. and Mrs. Smith is an original comedy, action and spy series from Amazon Studios. The story tells the story of John (Donald Glover) and Jane (Maya Erskine), two strangers who abandoned their identities and old lives to become partners, not only in marriage, but also in espionage. Associated by a mysterious spy agency, the two are sent on new and dangerous missions. With each new mission, the couple's relationship also goes through profound changes. But it's when their relationship presents new feelings that they need to show that they are not only skilled in the missions, but also capable of saving their relationship, since divorce is not an option for two professional assassins.